Sheep phylogeography and domestication as inferred from complete genome sequences — ASN Events

Sheep phylogeography and domestication as inferred from complete genome sequences (#115)

Marina M Naval Sanchez 1 , Sean S McWilliam 1 , Antonio A Reverter 1 , Miguel M Perez-Enciso 2 , Nicholas N.J. Hudson 1 , James J. Kijas 1
  1. CSIRO, St Lucia, QLD, Australia
  2. Centre for Research in Agricultural Genomics (CRAG), CSIC-IRTA-UAB-UB Consortium, Bellaterra, Spain

The highly diverse plethora of domestic sheep breeds is the outcome of direct human selection in behavioural as well as productive traits such as meat, milk or wool. To explore the genomic relatedness of domestic sheep breeds we made use of whole-genome sequences of 68 domestic sheep from five world regions: Africa, Americas, Asia, Europe and the Middle East. SNP calling across breeds resulted in a total of 26 million SNPs across all samples, ranging from 22 to 25 million SNPs per individual. Asian and African populations contain a higher rate of heterozygosity (32.3% and 28.4%) compared to breeds in Europe (19.9%), Americas (19.4%) and UK (20.4%). This is most likely a consequence of the sheep reference genome being from a European breed. In future, we aim to compare these genomes against wild ovids to give further insight into the genomic mechanisms underlying domestication across breeds as well as their functional implications.

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