Effects of <em>TEX11</em> and <em>AR</em> polymorhisms on reproduction and growth traits in Australian beef cattle — ASN Events
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  2. Concurrent 6 - Detecting casual variants I
  3. Effects of TEX11 and AR polymorhisms on reproduction and growth traits in Australian beef cattle

Effects of TEX11 and AR polymorhisms on reproduction and growth traits in Australian beef cattle (#33)

Loan To Nguyen 1 , Grego'rio M F de Camargo 2 , Russell E Lyons 3 , Sigrid A Lehnert 4 , Stephen S Moore 5 , Marina R S Fortes 1
  1. School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD 4072, Australia
  2. Departmento de Zootecnia, Universidade Estadual Paulista, Jaboticabal-SP, 14884-900, Brazil
  3. School of Veterinary Science, The University of Queensland, Gatton, 4343, Australia
  4. Queensland Bioscience Precinct, CSIRO Agriculture & Food, St Lucia, QLD, Australia
  5. Centre for Animal Science , Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, Brisbane, Qld 4072, Australia

Previous genome-wide association analyses indicated QTL regions located in X chromosome for scrotal circumference (SC) and percentage of normal sperm (PNS). The association between SNP in two potential candidate genes (TEX11 and AR) on chromosome X and observed phenotypic variation of SC and PNS were analysed. As expected from QTL findings, these SNP could explain more than 1% of the additive genetic variance for SC. Three SNP in TEX11 and a SNP in AR were significant for SC measurements taken at 12, 18 and 24 months of age. SNP in exon 1 of TEX11 gene had extremely significant effects on SC12, SC18 and SC24 with P-values ranging from 10-39 to 10-46. An association between a SNP in TEX11 and weight measurements was also identified. Associations reported herein suggest that these SNP in TEX11 and AR might aid genomic selection for SC and weight if included in genotyping panels.

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